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Drug information

Alfentanil

POM
Read time: 16 mins
Last updated: 06 May 2020
Published: 01 Apr 2021

4.1 Therapeutic indications

Alfentanil 5 mg/ml solution for injection is a potent opioid analgesic with a very rapid onset of action.

It is indicated for analgesia and suppression of respiratory activity in mechanically ventilated patients on intensive care and to provide analgesic cover for painful manoeuvres. It will aid compliance with mechanical ventilation, and tolerance of the endotracheal tube. Intravenous bolus doses of Alfentanil (0.5 mg/ml) may be used to provide additional pain relief during brief painful procedures such as physiotherapy, endotracheal suction, etc. Despite being mechanically ventilated, patients may be awake in the presence of adequate analgesia.

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).