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Drug information


Read time: 32 mins
Last updated: 06 May 2020
Published: 01 Apr 2021

4.1 Therapeutic indications

Methotrexate 2mg/ml Oral Solution is indicated in the following oncological indications:

• The maintenance treatment of Acute Lymphocytic Leukaemia (ALL) in children and adults.

• The treatment of malignant trophoblastic tumours

Methotrexate 2mg/ml Oral Solution is indicated in:

• The treatment of severe active rheumatoid arthritis in adults.

• Polyarthritic forms of active, severe juvenile idiopathic arthritis (JIA) in adolescents and children aged 3 years and over when the response to non-steroidal anti-inflammatory drugs (NSAIDs) has been inadequate.

• The treatment of severe forms of psoriasis vulgaris including chronic plaque psoriasis, erythrodermic psoriasis, psoriatic arthritis and pustular psoriasis which are not responsive to other conventional therapies such as phototherapy, PUVA and retinoids.

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Drug Licencing

Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).