4.1 Therapeutic indications
Anagrelide is indicated for the reduction of elevated platelet counts in at risk essential thrombocythaemia (ET) patients who are intolerant to their current therapy or whose elevated platelet counts are not reduced to an acceptable level by their current therapy.
An at-risk patient
An at risk essential thrombocythaemia patient is defined by one or more of the following features:
• >60 years of age or
• a platelet count > 1000 x 109/l or
• a history of thrombo-haemorrhagic events.
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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).