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Read time: 19 mins
Last updated: 28 Sep 2020
Published: 28 Sep 2020

4.1 Therapeutic indications

Itraconazole oral solution is indicated:

For the treatment of oral and/or oesophageal candidosis in HIV-positive or other immunocompromised patients.

As prophylaxis of deep fungal infections anticipated to be susceptible to itraconazole, when standard therapy is considered inappropriate, in patients with haematological malignancy or undergoing bone marrow transplant, and who are expected to become neutropenic (ie < 500 cells/µl). At present there are insufficient clinical efficacy data in the prevention of aspergillosis.

Consideration should be given to national and/or local guidance regarding the appropriate use of antifungal agents.

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Drug Licencing

Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).