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Drug information

Metronidazole

POM
Read time: 10 mins
Last updated: 16 Oct 2020
Published: 16 Oct 2020

4.1 Therapeutic indications

Metronidazole Tablets 200mg is indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause.

Metronidazole Tablets 200mg is active against a wide range of pathogenic micro- organisms, notably species of Bacteroides, Fusobacteria, Clostridia, Eubacteria, anaerobic cocci and Gardnerella vaginalis.

It is also active against Trichomonas vaginalis and other species of trichomonads, Entamoeba histolytica, Giardia lamblia, Balantidium coli and the causative organisms of acute ulcerative gingivitis.

Metronidazole Tablets 200mg is indicated in the oral treatment of:

The prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic streptococci.

The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis and post- operative wound infections from which pathogenic anaerobes have been isolated.

Urogenital trichomoniasis in the female (trichomonal vaginitis) and in the male. The male consort of females suffering from urogenital trichomoniasis should be treated concurrently.

Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or

Gardnerella vaginitis).

All forms of amoebiasis (intestinal and extra-intestinal disease, and that of symptomless cyst passers).

Giardiasis.

Acute ulcerative gingivitis.

Anaerobically-infected leg ulcers and pressure sores.

Acute dental infections (e.g. acute pericoronitis and acute apical infections). Considerations should be given to official guidance on the appropriate use of antibacterial agents.

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Drug Licencing

Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).