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Drug information


Read time: 24 mins
Last updated: 06 May 2020
Published: 27 Apr 2021

4.1 Therapeutic indications

Amiodarone hydrochloride is indicated for the treatment of serious cardiac arrhythmias, in cases where other therapies are not effective or contraindicated:

- atrial arrhythmias, including atrial fibrillation or flutter

- AV nodal arrhythmias and AV reentrant tachycardia, e.g. as a manifestation of Wolff-Parkinson-White syndrome

- life-threatening ventricular arrhythmias, including persistent or non-persistent ventricular tachycardia or episodes of ventricular fibrillation

Amiodarone Hydrochloride 50 mg/ml Concentrate for Solution for Injection/Infusion can be used where a rapid response is required or where oral administration is not possible.

Amiodarone hydrochloride may be used prior to DC cardioversion.

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).