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Read time: 8 mins
Last updated: 06 May 2020
Published: 24 Jul 2020

4.1 Therapeutic indications

Atropine sulfate 3 mg/10 ml, solution for injection in pre-filled syringe is indicated in adults only.

- As a pre-anaesthetic medication: to prevent vagal reactions associated with tracheal intubation and surgical manipulation.

- To limit the muscarinic effects of neostigmine, when given postsurgically to counteract non-depolarising muscle relaxants

- Treatment of hemodynamically compromising bradycardia and/ or atrioventricular block due to excessive vagal tone in emergency situation

- Cardiopulmonary resuscitation: to treat symptomatic bradycardia and AV block.

- As antidote following overdosage or poisoning with acetylcholinesterase-inhibitors e.g. anticholinesterases, organophosphorus, carbamates and muscarinic mushrooms.

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