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Idiopathic Pulmonary Fibrosis: Epidemiology, Natural History, Phenotypes.
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias. It is characterized by a chronic, progressive, fibrotic interstitial lung disease of unknown cause that occurs primarily in older adults.
Oxidant/Antioxidant Disequilibrium in Idiopathic Pulmonary Fibrosis Pathogenesis.
Idiopathic pulmonary fibrosis is characterised by abnormal reepithelialisation and remodelling consequent to persistent stimuli or injury. The involvement of oxidative stress in alveolar injury, inflammation and fibrosis development...
Idiopathic pulmonary fibrosis: the radiologist's role in making the diagnosis.
Radiologists have a critical role in the evaluation and diagnosis of suspected idiopathic pulmonary fibrosis (IPF). Accurate pattern identification on imaging is key in the multidisciplinary diagnostic process and frequently obviates...
Telomere Abnormalities in the Pathobiology of Idiopathic Pulmonary Fibrosis.
Idiopathic pulmonary fibrosis (IPF) occurs primarily in older adults and the incidence is clearly associated with aging. This disease seems to be associated with several hallmarks of aging, including telomere attrition and cellular senescence.
Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.
Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically significant, respiratory deterioration of unidentifiable cause. The objective of this international working group report on acute...
Under-recognised co-morbidities in idiopathic pulmonary fibrosis: A review.
Co?morbidities in idiopathic pulmonary fibrosis are common. These co?morbidities include obstructive sleep apnoea, gastro?oesophageal reflux disease, pulmonary hypertension and depression. The presence of co?morbidities...
Overview of idiopathic pulmonary fibrosis, evidence-based guidelines, and recent developments in the treatment landscape.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive-fibrosing interstitial lung disease of unknown origin that affects 3 million people worldwide and imparts substantial burdens to patients, their families, and the healthcare system.