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Merck Inc. has announced that The Lancet and Clinical Infectious Diseases have published online the results from the pivotal Phase...

This is a Phase 3, multicenter, prospective, randomized, double-blind, double dummy study of CXA 201 IV infusions (1500 mg q8h)...

To demonstrate the non-inferiority of CXA-201 versus comparator (levofloxacin) in adult subjects with cUTI (including pyelonephritis) based on the difference...

Levofloxacin 5 mg/ml Solution for Infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Community-acquired pneumonia, • Complicated skin and soft tissue infections/Complicated skin and skin structure infections. In Complicated skin and soft tissue infections/Complicated skin and skin structure infections, Levofloxacin 5 mg/ml Solution for Infusion should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4); • Chronic bacterial prostatitis; • Inhalation Anthrax: post-exposure prophylaxis and curative treatment (see section 4.4). Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 5 mg/mL Solution for infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Community-acquired pneumonia • Complicated skin and soft tissue infections For the above-mentioned infections Levofloxacin 5 mg/mL Solution for infusion should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4). Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 500mg Film-coated Tablets is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis • Uncomplicated cystitis (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis • Complicated skin and soft tissue infections/complicated skin and skin structure infections For the above-mentioned infections Levofloxacin 500mg Film-coated Tablets should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Community-acquired pneumonia • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4) Levofloxacin 500mg Film-coated Tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Community-acquired pneumonia • Complicated skin and soft tissue infections / Complicated skin and skin structure infection.For the above-mentioned infections, Levofloxacin tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Uncomplicated cystitis (see section 4.4) In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis. In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections Levofloxacin tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Community-acquired pneumonia • Complicated skin and soft tissue infections / Complicated skin and skin structure infection.For the above-mentioned infections, Levofloxacin tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Uncomplicated cystitis (see section 4.4) In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis. In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections Levofloxacin tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 250mg Film-coated Tablets is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis • Uncomplicated cystitis (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis • Complicated skin and soft tissue infections/complicated skin and skin structure infections For the above-mentioned infections Levofloxacin 250mg Film-coated Tablets should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Community-acquired pneumonia • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4) Levofloxacin 250mg Film-coated Tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin Tablets is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis • Acute exacerbation of chronic obstructive pulmonary disease including bronchitisUncomplicated cystitis (see section 4.4) • Community-acquired pneumonia • Complicated skin and soft tissue infections For the above-mentioned infections Levofloxacin Tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the initial treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4)Chronic bacterial prostatitis • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4) Levofloxacin Tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.