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Merck Inc. has announced that The Lancet and Clinical Infectious Diseases have published online the results from the pivotal Phase...

In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Community-acquired pneumonia • Complicated skin and soft tissue infections / Complicated skin and skin structure infection.For the above-mentioned infections, Levofloxacin tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Uncomplicated cystitis (see section 4.4) In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis. In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections Levofloxacin tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 5 mg/ml Solution for Infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Community-acquired pneumonia, • Complicated skin and soft tissue infections/Complicated skin and skin structure infections. In Complicated skin and soft tissue infections/Complicated skin and skin structure infections, Levofloxacin 5 mg/ml Solution for Infusion should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4); • Chronic bacterial prostatitis; • Inhalation Anthrax: post-exposure prophylaxis and curative treatment (see section 4.4). Consideration should be given to official guidance on the appropriate use of antibacterial agents.

In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): In adults, Levofloxacin tablets are indicated for the treatment of the following infections (see sections 4.4 and 5.1): • Acute bacterial sinusitis In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Community-acquired pneumonia • Complicated skin and soft tissue infections / Complicated skin and skin structure infection.For the above-mentioned infections, Levofloxacin tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Uncomplicated cystitis (see section 4.4) In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4) • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis. In above-mentioned infections, Levofloxacin tablets product should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections Levofloxacin tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 5 mg/mL Solution for infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Community-acquired pneumonia • Complicated skin and soft tissue infections For the above-mentioned infections Levofloxacin 5 mg/mL Solution for infusion should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4). Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin 5 mg/ml solution for infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • In Complicated skin and soft tissue infections / Complicated skin and skin structure infections Levofloxacin 5 mg/ml should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Community-acquired pneumonia • Acute pyelonephritis and complicated urinary tract infections (see section 4.4). • Chronic bacterial prostatitis. • Inhalation Anthrax: postexposure prophylaxis and curative treatment (see section 4.4). Consideration should be given to official guidance on the appropriate use of anti-bacterial agents

Levofloxacin Ibigen solution for infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Community-acquired pneumonia • Complicated skin and soft tissue infections In complicated skin and soft tissue infections Levofloxacin Ibigen should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4) Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Levofloxacin solution for infusion is indicated in adults for the treatment of the following infections (see sections 4.4 and 5.1): • Acute pyelonephritis and complicated urinary tract infections (see section 4.4) • Chronic bacterial prostatitis. • Inhalation Anthrax: post exposure prophylaxis and curative treatment (see section 4.4). In the below mentioned indications levofloxacin should be used only when it is considered inappropriate to use other antibacterial agents that are commonly recommended for the treatment of these infections. • Community-acquired pneumonia. • Complicated skin and soft tissue infections Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Patients with cystic fibrosis (CF) suffer from chronic infections of the lower respiratory tract that can be caused by one or multiple bacteria, including Pseudomonas aeruginosa, which has been particularly problematic to eradicate and been implicated as the major cause of morbidity and mortality in CF patients.

Tetraphase Pharmaceuticals announced that the IGNITE2 phase III clinical trial of eravacycline administered as an IV-to-oral transition therapy for the...