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Journal
07/06/16

Molecularly targeted drugs plus radiotherapy and temozolomide treatment for newly diagnosed glioblastoma: A meta-analysis and systematic review.

Glioblastoma (GBM) is the most common primary malignant brain tumor that nearly always results in a bad prognosis.

  • 1 min read
  • Source: Oncology Research
Clinical trial
01/01/16

Study of Nivolumab Versus Temozolomide, Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate 498)

The main purpose of this study is to compare how long patients with glioblastoma (GBM, a malignant brain cancer) live...

  • 1 min read
  • Source: Clinicaltrials.gov
Clinical trial
01/11/11

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

This 2-arm, randomized, phase III study will investigate the efficacy and safety of the addition of rindopepimut (an experimental cancer...

  • 1 min read
  • Source: Clinicaltrials.gov
Clinical trial
26/08/14

Prevention of Thrombocytopenia in Glioblastoma Patients (PLATUM)

Chemotherapy used in the treatment of primitive tumors of the central nervous system has a particularly important platelet toxicity compared...

  • 2 min read
  • Source: Clinicaltrials.gov
Drug news
02/06/15

NovoCure announces results of Phase III trial of Tumor Treating Fields + temozolomide for glioblastoma.

Novocure, a commercial stage oncology company, announced that the first analysis of all 700 newly diagnosed glioblastoma (GBM) patients enrolled...

  • 1 min read
Journal
29/05/18

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed dendritic cell vaccine (DCVax®-L) to standard therapy for newly diagnosed glioblastoma.

  • 1 min read
  • Source: Journal of Translational Medicine
Clinical trial
14/06/10

Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients

The prognosis of patients with newly diagnosed glioblastoma is dismal despite recent therapeutic improvements Using standard therapy with temozolomide (TMZ)...

  • 2 min read
  • Source: National Cancer Institute
Drug news
02/02/18

Phase III trial results for Optune in glioblastoma published in JAMA Oncology.- Novocure.

Novocure announced that a detailed quality of life analysis of Novocure�s EF-14 phase III pivotal trial of Optune in combination...

  • 1 min read
Drug news
17/11/14

Success in Phase III trial of NovoTTF-100A for Brain Cancer - Novocure

Novocure has announced that the NovoTTF-100A System (tumor treating fields therapy) in combination with standard-of-care temozolomide chemotherapy extended both progression-free...

  • 1 min read
Drug news
07/12/18

EF-14 phase III trial of Optune in glioblastoma published in Journal of Neuro-Oncology.- Novocure.

Novocure announced that the results of a retrospective post-hoc sub-group analysis of its EF-14 phase III pivotal trial in newly...

  • 1 min read
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