Psoriasis Treatment
Learn about the inflammatory pathways involved in disease initiation and progression and the latest updates on treatments for moderate-to-severe psoriasis, including:
- Psoriasis pathophysiology in our expert interview with Professor Stefano Piaserico
- Key clinical trial results of available systemic and biologic treatments
- Recent long-term efficacy and safety data with Professor Diamant Thaçi
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Psoriasis is associated with epidermal thickening and keratinocyte hyperproliferation. As a result, the skin becomes inflamed and has raised plaques with silvery scales, which can cover large areas of the body (Nestle et al., 2009; Boehncke & Schön, 2015; Palfreeman et al., 2013).
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Systemic and biologic treatments
For patients with milder disease, first-line psoriasis treatment often involves topical therapies including corticosteroids, vitamin D3 analogues, and combination products. However, patients with moderate to severe and refractory symptoms may be candidates for systemic therapy (Kim et al., 2017).
In a survey conducted in the United States, Canada, France, Germany, Italy, Spain, and the United Kingdom, dermatologists reported that among patients with moderate to severe psoriasis, approximately 75% of patients were receiving topical therapy, 20% of patients were receiving conventional oral therapy and 20% of patients were receiving biologics (Feldman et al., 2016a).
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Develop your knowledge with our disease and condition focused Learning Zones
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Key research and clinical data
Psoriasis-related publications have grown substantially since 1960 and recent discoveries have paved the way for future research. Although research topics have expanded and diversified, the goal of research has remained to better understand psoriasis and its treatment to benefit patients living with the disease (Sako, 2016).
The ever-changing psoriasis therapeutic landscape makes it particularly important to not only acknowledge the efficacy and safety of treatments in clinical trials, but also to consider results from long-term registry-based observational studies (Altenburg et al., 2018).
Why sign up with Medthority?
Develop your knowledge with our disease and condition focused Learning Zones
Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines
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Why sign up with Medthority?
Develop your knowledge with our disease and condition focused Learning Zones
Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines
Personalised dashboard providing updates and recommendations for content within your areas of interest
Why sign up with Medthority?
Develop your knowledge with our disease and condition focused Learning Zones
Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines
Personalised dashboard providing updates and recommendations for content within your areas of interest
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Developed by EPG Health for Medthority. This content has been developed independently of the sponsor Almirall S.A, who have had no editorial input into the content. EPG Health received educational funding from the sponsor in order to help provide its healthcare professional members with access to the highest quality medical and scientific information, education and associated relevant content.