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Optimising anti-TNF treatment using biosimilars

Decision Making

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Shared decision making (SDM) between physicians and patients, as opposed to HCPs making decisions on behalf of patients without proper information and consent, is supported by a growing base of evidence across a range of therapy areas from rheumatologic disease to cancer.1 So, how can SDM boost treatment adherence and persistence for biologics and/or biosimilars?

 

 

Studies show that when patients have an active involvement in treatment decisions and are more educated about their treatment they will elect for more conservative treatment options.2 Patients who adhere to their treatments are three times more likely to achieve desired outcomes, such as improved quality of life and better functional capacity, than nonadherent patients.3 When HCPs and patients engage in SDM there is a greater likelihood of adherence for patients, often with the added bonus of reduced health care costs.3 Health care costs attributable to nonadherence annually in the United States are estimated to be $100–$300 billion per year.4

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How biosimilars are changing exit strategies with anti-TNF therapy

The increasing numbers of anti-TNF biosimilars available on the market represent increasing treatment options for patients and potentially improved rates of remission. HCPs are starting to re-evaluate the need of applying exit strategies for anti-TNF therapy with the reduced costs of these treatments, following the advent of biosimilars.

For each major class of treatment used alone or in combination, there is a risk of relapse following dose reduction or stopping of treatment.22 Generally, patients in clinical, biochemical and endoscopic remission have an increased chance of maintaining health when treatments are stopped.22 Whether or not to stop a treatment depends on each individual patient and SDM with the patient should take place.22 

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References

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