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Verquvo is approved in China by NMPA to treat patients with chronic heart failure and reduced ejection fraction.

Read time: 1 mins
Published:31st May 2022

Bayer announced that China’s National Medical Products Administration (NMPA) has approved vericiguat under the brand name Verquvo.

Verquvo (2.5 mg, 5 mg, and 10 mg), a soluble guanylate cyclase (sGC) stimulator, is indicated in China to reduce the risk of heart failure (HF) hospitalization or requiring intravenous (IV) diuretics in emergency, in adults with symptomatic chronic HF and reduced ejection fraction (less than 45%) who are stabilized after a recent decompensation event with IV therapy.

It works differently to existing heart failure treatments, providing a specific approach to managing chronic heart failure after a recent decompensation event with IV therapy, also known as a worsening heart failure event.

Current therapies block the harmful effects of the natural neurohormonal systems that are activated by the myocardial and vascular dysfunction present in heart failure. Verquvo works through a different mode of action. It specifically restores the deficient NO-sGC-cGMP pathway, which plays a critical role in the progression of heart failure and aggravating its symptoms. Verquvo was studied and approved on top of standard-of-care.

Condition: Heart Failure
Type: drug

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