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  • Breakthrough results for Jardiance confirm EMPEROR...

Breakthrough results for Jardiance confirm EMPEROR-Preserved as first and only successful trial for heart failure with preserved ejection fraction. Eli Lilly + Boehringer.

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Published:7th Jul 2021
The EMPEROR-Preserved phase III trial met its primary endpoint, establishing Jardiance (empagliflozin) from Eli Lilly and Boehringer, as the first and only therapy to significantly reduce the risk of the composite of cardiovascular death or hospitalization for heart failure in adults, with or without diabetes, who live with heart failure with preserved ejection fraction (HFpEF).

Boehringer Ingelheim and Eli Lilly and Company announced the topline results. When added to the EMPEROR-Reduced trial results, these findings demonstrate Jardiance's efficacy in all forms of heart failure regardless of ejection fraction. The safety profile was generally consistent with the known safety profile of Jardiance.

The EMPEROR-Preserved trial investigated Jardiance 10 mg compared with placebo. Full results from the EMPEROR-Preserved trial are scheduled for presentation at the European Society of Cardiology (ESC) Congress 2021 on August 27. Boehringer Ingelheim and Lilly plan for regulatory submissions in 2021.

Condition: Heart Failure
Type: drug

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