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Journal

Relationship between knee alignment and T1? values of articular cartilage and menisci in patients with knee osteoarthritis

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Published:25th Mar 2020

Objective:

To assess the relationship between knee alignment and subregional T1? values of the femorotibial cartilage and menisci in patients with mild (Kellgren´┐ŻLawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3 T.

Materials and methods:

26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3 T MR scanner. Mann´┐ŻWhitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1? values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.

Results:

Medial femoral anterior cartilage subregion in varus group had significantly higher (p < 0.05) T1? values than all cartilage subregions in valgus group. Medial tibial central cartilage subregion had significantly higher T1? values (p < 0.05) than lateral tibial central cartilage subregion in varus group. The posterior horn of the medial meniscus in neutral group had significantly higher T1? values (p < 0.0029) than all meniscus subregions in valgus group. Conclusion: There exists some degree of association between knee alignment and subregional T1? values of femorotibial cartilage and menisci in patients with clinical OA.

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