This site is intended for healthcare professionals
  • Home
  • /
  • Journals
  • /
  • Uncategorised Disease
  • /
  • Geriatric Syndromes increased the Nutritional Risk...

Geriatric Syndromes increased the Nutritional Risk in Elderly Cancer Patients Independently from Tumor Site and Metastatic Status. The ELCAPA-05 Cohort Study.

Read time: 1 mins
Published:25th Mar 2020
Background & Aims: We assessed the prevalence and risk factors of malnutrition in elderly cancer patients. Methods: We studied a prospective cohort of solid cancer patients aged ?70 years at referral to two geriatric oncology clinics between 2007 and 2010. Nutrition was evaluated using the Mini-Nutritional Assessment (MNA) using validated cut-offs (<17: malnutrition, 17-23.5: at-risk for malnutrition). patients with non-digestive tumours (breast, prostate, urinary tract) and with digestive (colorectal, upper digestive tract and liver) were analysed separately using multinomial logistic regression results: of 643 consecutive patients, 519 had available data (median age, 80; men, 48.2%; metastases, 46.3%; digestive cancer 47.8%). in non-digestive group, 13.3% had malnutrition versus 28.6% in digestive group. the link between metastasis and malnutrition was significantly higher in non-digestive group (adjusted odds ratio [ora ], 25.25; 95%ci: 5.97-106.8) than in digestive group (ora, 2.59; 1.08-6.24; p for heterogeneity="0.04)." other factors independently associated with malnutrition were cognitive impairment (orammmse ? 24 versus> 24 in non-digestive group: 16.68; 4.89-56.90 and in digestive group: 3.93;1.34-11.50), and depressed mood (ORa MiniGDS ?1 versus <1 in non-digestive group:11.11; 3.32-37.17 and in digestive group: 3.25; 1.29-8.15) and fall risk (ora fall risk versus no fall risk in non-digestive group: 4.68; 1.77-12.37 ; in digestive group: 100% of malnourished patients were faller´┐Żs). conclusion: we highlighted, in elderly cancer patients, the high prevalence of malnutrition and that geriatrics syndromes (i.e. cognitive impairment, depressed mood and fall risk) were independent risk factors for malnutrition. moreover, metastatic status was significantly much more strongly associated with malnutrition in non-digestive than digestive tumours>

Read abstract on library site