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Indacaterol/glycopyrronium: a dual bronchodilator for COPD.

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Published:1st Jan 2018
Author: Banerji D, Fogel R, Patalano F.
Availability: Free full text
Ref.:Drug Discov Today. 2018;23(1):196-203.

Indacaterol/glycopyrronium (IND/GLY) 110/50mcg was the first once-daily, long-acting β2-agonist (LABA)/long-acting muscarinic antagonist (LAMA) fixed-dose combination (FDC) approved in Europe for the treatment of chronic obstructive pulmonary disease (COPD). Development of IND/GLY was driven by the need to improve the standard of care for patients with this disease, in terms of symptom control and exacerbation frequency. IGNITE, an adaptive, comprehensive, and innovative Phase 3 development program, demonstrated the efficacy of IND/GLY in optimising bronchodilation, reducing symptoms, and reducing exacerbations in patients with COPD.

IGNITE challenged contemporary thinking about the pharmacological treatment and management of patients with this disease.


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