The gene for the glucocorticoid receptor regulator FK506 binding protein 5 (FKBP5) plays a role for risk, response to treatment and changes in brain areas in major depressive disorder (MDD).
Purpose of review: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and heterogeneous inflammatory disease. The underlying epigenetic mechanisms and treatment of CRSwNP are partially understood.
Advanced parental age might constitute a generic risk factor for mental and somatic disorders.
Osteoarthritis (OA) is progressive disease characterised by cartilage degradation, subchondral bone remodelling and inflammation of the synovium.
Systemic lupus erythematosus (SLE) is a life-threatening autoimmune disease that is characterized by dysregulated dendritic cells, T and B cells, and abundant autoantibodies.
Knowing how dramatically genetic mutations can influence cancer risk so researchers investigated whether there is a gene on the X chromosome that influences the risk of developing ovarian cancer.
Psoriasis is a chronic inflammatory skin disease whose prevalence varies among different populations worldwide.
Objective: Exposure therapy is an effective treatment for posttraumatic stress disorder (PTSD), but many patients do not respond. Brain functions governing treatment outcome are not well characterized.
The importance of epigenetics has increased due to identification of its role in the pathophysiology of a number of diseases including allergic rhinitis. Amongst the different epigenetic changes in allergic retinitis, deacetylation...