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Improving treatment options for childhood psoriasis
Declaration of sponsorship Novartis Pharma AG

What's wrong with Mia?

Declaration of sponsorship Novartis Pharma AG
Read time: 40 mins
Last updated:12th Feb 2021
Published:4th Jul 2020
Discover the burden of childhood psoriasis and the many important things to consider when treating young patients like Mia. Children suffering with psoriasis should certainly not be treated as little adults and while their future health depends on effective early treatment, physicians currently have limited treatment options.
  • Join Mia on her animated journey to appreciate how you can improve the lives of young people like her
  • Appreciate the burden of psoriasis to help those living with its challenges

What is life like for Mia and her family?

Let’s meet our patient Mia and her family who are going to help us understand the impact of moderate to severe psoriasis for all the family. 

Note: Mia is an expert-reviewed theoretical case for educational purposes only.  

In this introductory animation, Mia’s worried parents take her to see a new paediatric dermatologist. Mia has continued to put on weight and become increasingly withdrawn at school and depressed and so she has been referred by her primary care physician.

Find out about the treatments that Mia has tried in the past in the next section of the Learning Zone

Keep reading to find out about the complexities of diagnosing and treating childhood psoriasis.

Psoriasis is common in children and they may need lifelong treatment

The prevalence of psoriasis in children is difficult to determine as many cases are either missed or misdiagnosed and it varies by age, gender, psoriasis definition, study design and geographical region1.

PaedDerma_Pt1_Fig1.png

Figure 1. Range of childhood psoriasis prevalence (percentage of population) (adapted from Burden-Teh et al.2).

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Diagnosing psoriasis and measuring QoL is more difficult in children

Diagnosis

Although the clinical subtypes of psoriasis in children are similar to adults, diagnosis in children is more challenging.

In a study of 887 patients <18 years, the most common subtypes of psoriasis were7:

  • plaque psoriasis (73.7%)
  • guttate psoriasis (13.7%)
  • scalp psoriasis (7.6%)
  • pustular psoriasis (1.1%)
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Develop your knowledge with our disease and condition focused Learning Zones

Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines 

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Comorbidities are often present in childhood psoriasis

Children with psoriasis are at greater risk of obesity, diabetes, anxiety and depression and show marked impairment in emotional, social and school functions25–27.

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Why sign up with Medthority?

Develop your knowledge with our disease and condition focused Learning Zones

Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines 

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Treatment data and options are more limited in childhood psoriasis

There are a plethora of treatments available for adults with moderate-to-severe-psoriasis but a lack of efficacy and safety data in paediatric populations means there are far fewer approved treatments available to children and widespread off-label use34

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Why sign up with Medthority?

Develop your knowledge with our disease and condition focused Learning Zones

Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines 

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References

 

  1. World Health Organization. Psoriasis. 2016. Available at: https://www.who.int/publications-detail/global-report-on-psoriasis. Accessed 27 April 2020.
  2. Paller AS, Singh R, Cloutier M, Gauthier-Loiselle M, Emond B, Guérin A, et al. Prevalence of psoriasis in children and adolescents in the United States: A claims-based analysis. J Drugs Dermatology. 2018;17(2):187–194.
  3. Bronckers IMGJ, Paller AS, van Geel MJ, van de Kerkhof PCM, Seyger MMB. Psoriasis in children and adolescents: Diagnosis, management and comorbidities. Pediatric Drugs. 2015;17(5):373–384.
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Why sign up with Medthority?

Develop your knowledge with our disease and condition focused Learning Zones

Access content from credible sources, including expert-led commentary, videos, podcasts, and webinars as well as clinical trials, treatment information and guidelines 

Personalised dashboard providing updates and recommendations for content within your areas of interest

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