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Guidelines for the safe and effective prescribing of azathioprine 2011

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Last updated:21st Jul 2011
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the safe and effective use of azathioprine. The document aims to update and expand on the previous guidelines by (i) offering a complete reappraisal of all relevant literature since 1966 and focusing on key developments over the past 5 years, in particular the applicability of thiopurine methyltransferase (TPMT) assessment to the clinical setting; (ii) addressing important, practical clinical questions
relating to the primary guideline objective; (iii) providing guideline recommendations with an evaluation of their health economic impact; and (iv) discussing potential developments and future directions. The guideline is presented as a detailed review with highlighted recommendations for practical use in the clinic, in addition to updated patient information.

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