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Fibrinogen Deficiency in Bleeding Learning Zone

Fibrinogen concentrate and risk of thromboembolic complications

Does fibrinogen concentrate increase the risk of thromboembolic complications and death when given to bleeding cardiac patients?

Fibrinogen concentrate is recommended as a replacement therapy in patients with major bleeding following surgery since it is one of the first coagulation factors to fall to critically low levels during ongoing bleeding (Hiippala et al., 1995; Kozek-Langenecker et al., 2017; Pagano et al., 2018; Spahn et al., 2019).

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