In this learning zone, we highlight that acquired fibrinogen deficiencies are much more common than congenital deficiencies. Acquired fibrinogen deficiency is usually the result of consumption, dilution or loss through bleeding as occurs during massive trauma, cardiac surgery and postpartum haemorrhage. Learn more about both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger levels for treatment and treatment options.
Fibrinogen deficiency is a clinical challenge for bleeding management. We discuss both congenital and acquired fibrinogen deficiencies.
Read about techniques used in the clinic to measure the quantity and quality of fibrinogen and the available data on point–of–care devices.
Here we compare fibrinogen concentrate with fresh frozen plasma and cryoprecipitate for treating fibrinogen deficiencies in different clinical contexts.
The Publication Digests section of this Learning Zone provides simplified detail and graphical summaries of the latest relevant published literature related to fibrinogen replacement treatments.
Video footage from the ISICEM 2019, featuring topics such as trauma induced coagulopathy and the critical reduction of fibrinogen, can be found below.