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Drug information

Alendronic acid

POM
Read time: 19 mins
Last updated: 06 May 2020
Published: 24 Jul 2020

4.1 Therapeutic indications

• Treatment of postmenopausal osteoporosis. Alendronic acid reduces the risk of vertebral and hip fractures.

• Treatment of osteoporosis in men at increased risk of fracture. A reduction in the incidence of vertebral, but not of non-vertebral fractures has been demonstrated.

• Prophylaxis of glucocorticoid-induced osteoporosis.

Risk factors often associated with the development of osteoporosis include thin body build, family history of osteoporosis, early menopause, moderately low bone mass and long-term glucocorticoid therapy, especially with high doses (15 mg/day).

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).