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Read time: 20 mins
Last updated: 06 May 2020
Published: 01 Apr 2021

4.1 Therapeutic indications

Fluorouracil is indicated in adults.

Fluorouracil is indicated in the treatment of the following malignancies and disease settings:

- in the treatment of metastatic colorectal cancer

- as adjuvant treatment in colon and rectal cancer

- in the treatment of advanced gastric cancer,

- in the treatment of advanced pancreatic cancer,

- in the treatment of advanced oesophageal cancer,

- in the treatment of advanced or metastatic breast cancer,

- as adjuvant treatment in patients with operable primary invasive breast cancer,

- in the treatment of inoperable locally advanced squamous cell carcinoma of the head and neck in previously untreated patients

- in the treatment of locally recurrent or metastatic squamous cell carcinoma of the head and neck

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Drug Licencing

Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).