4.1 Therapeutic indications
Treatment of infections due to sensitive Gram-positive organisms, including infections caused by β-lactamase-producing Staphylococci and Streptococci.
Typical indications include:
Skin and soft tissue infections:
Protection for skin grafts
Infected skin conditions e.g. ulcers, eczema and acne.
Respiratory tract infections:
Otitis media and externa
Other infections caused by flucloxacillin-sensitive organisms:
Urinary tract infection
Flucloxacillin is also indicated for use as a prophylactic during major surgical procedures such as cardiothoracic and orthopaedic surgery. Parenteral usage is indicated where oral dosage is inappropriate.
Consideration should be given to official local guidance (e.g. national recommendations) on the appropriate use of antibacterial agents.
Susceptibility of the causative organism to the treatment should be tested (if possible), although therapy may be initiated before the results are available.
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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).