4.1 Therapeutic indications
Dobutamine 12.5 mg/ml concentrate for solution for infusion is indicated in adults who require inotropic support in the treatment of low output cardiac failure associated with myocardial infarction, open heart surgery, cardiomyopathies, septic shock and cardiogenic shock. Dobutamine 12.5 mg/ml concentrate for solution for infusion can also increase or maintain cardiac output during positive end expiratory pressure (PEEP) ventilation.
Dobutamine stress echocardiography
(Adult population only)
Dobutamine 12.5 mg/ml concentrate for solution for infusion may also be used for cardiac stress testing as an alternative to exercise in patients for whom routine exercise cannot be satisfactorily performed. This use of dobutamine should only be undertaken in units which already perform exercise stress testing and all normal care and precautions required for such testing are also required when using dobutamine for this purpose.
Dobutamine is indicated in all paediatric age groups (from neonates to 18 years of age) as inotropic support in low cardiac output hypoperfusion states resulting from decompensated heart failure, following cardiac surgery, cardiomyopathies and in cardiogenic or septic shock.
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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).