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Drug information

Esomeprazole

POM
Read time: 24 mins
Last updated: 06 May 2020
Published: 24 Jul 2020

4.1 Therapeutic indications

Esomeprazole Gastro-resistant tablets are indicated in adults for:

Gastroesophageal Reflux Disease (GERD)

- treatment of erosive reflux esophagitis

- long-term management of patients with healed esophagitis to prevent relapse

- symptomatic treatment of gastroesophageal reflux disease (GERD)

In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori and

- healing of Helicobacter pylori associated duodenal ulcer and

- prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers

Patients requiring continued NSAID therapy

- healing of gastric ulcers associated with NSAID therapy.

- prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk.

Prolonged treatment after I.V. induced prevention of rebleeding of peptic ulcers

Treatment of Zollinger Ellison Syndrome

Esomeprazole Gastro-resistant tablets are indicated in adolescents from the age of 12 years for:

Gastroesophageal Reflux Disease (GERD)

- treatment of erosive reflux esophagitis

- long-term management of patients with healed esophagitis to prevent relapse

- symptomatic treatment of gastroesophageal reflux disease (GERD)

In combination with antibiotics in treatment of duodenal ulcer caused by Helicobacter pylori

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).