We are delighted to announce that our keynote speaker will be Dr Gitta Stockinger,Senior Group Leader and Associate Research Director at the Francis Crick Institute, UK.
A session to highlight immunological investigations and vaccine developments against different tropical diseases.
The brainy immune system
This session will explore recent advances in our understanding of interactions between the neuronal and immune systems. Highlighting the role neuronal signalling plays in shaping the immune response in homeostasis and disease, and the key role of immune cells in neuronal health from gut to fat to lymphoid tissues.
Immunotherapies come of age
The session will draw together learnings from two decades of immunotherapy for immune diseases and, more recently, cancer. In particular, the session will focus on areas such as how useful were preclinical models, target pathway selection, optimising safety, biological monitoring, dose and administration regimen design and how this should inform the more recent approaches to immunotherapy.
Much of our understanding of the human immunity comes from studies investigating response in blood, drawing inference from other model systems. However, in the last decade approaches for directly sampling from tissues and getting more data from fewer cells has changed this. In this session, we will look at advances in directly sampling from lymph nodes and other tissues to draw more information about the human immune response.
Single cell technologies from scRNAseq and high dimensional cytometry to large scale human clinical trial datasets has opened new opportunities to understand mechanisms of human immune in health and disease and provided the capacity to apply machine learning and AI to transform mechanistic understanding and accelerate therapeutic development. This session will explore the frontiers of systems-based approaches to explore how it is impacting on immunology and clinical medicine.
Innate inborn immunodeficiencies (informing on immune function)
This session will look at how the identification of genetic mutations associated with disease can provide novel insights into unpredicted functions of innate immune sensory and regulatory molecules and pathways.