Clinical trial
Veliparib (ABT888) Monotherapy for Patients with BRCA germline mutation and Platinum-Resistant or Partially Platinum-Sensitive Relapse of Epithelial Ovarian Cancer
Phase I:
To determine:
� Maximum-tolerated dose (MTD)
� Dose-limiting toxicities (DLT)
� Recommended phase II dose
Phase II:
To investigate the response rate in platinum-resistant and partially platinum sensitive ovarian cancer patients with known BRCA mutations treated with veliparib monotherapy.
Category | Value |
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Study start date | 2011-07-29 |