The Role of Insulin Resistance in Patients With Heart Failure and Type 2 Diabetes (CARMET2)

The purpose of this cross-sectional comparative 2x2 trial study is to compare the degree of insulin resistance, myocardial function and selected metabolic parameters and to explore the pathophysiological mechanisms by which insulin resistance is implicated in development of chronic heart failure (HF) in patients with type 2 diabetes and prediabetes (T2D).

Investigators hypothesize that patients with heart failure will be insulin-resistant and will display metabolic abnormalities as patients with diabetes.

Study Type: Observational

Study Design: Time Perspective: Cross-Sectional

Official Title: The Role of Insulin Resistance in Patients With Heart Failure and Type 2 Diabetes

Estimated Enrollment: 100

Study Start Date: December 2013

Estimated Study Completion Date: December 2019

Estimated Primary Completion Date: December 2019 (Final data collection date for primary outcome measure)