The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of Prograf and Advagraf

The objectives of this study are 1) To determine the influence of CYP3A5 and ABCB1 genotypes on Advagraf pharmacokinetics 2) To compare the influence of these genotypes on the comparison between Prograf and Advagraf pharmacokinetics