Renal PRotection Against Contrast mEdium-induced nephroPathy in High Risk Patients undErgoing Coronary Angiography (PREPARE)

This study evaluates the efficacy of remote ischemic preconditioning on preventing contrast medium-induced nephropathy in a population of high risk patients undergoing coronary angiography. Half of participants will receive a preconditioning procedure while the other half will receive a sham procedure.

Study Type: Interventional

Allocation: Randomized

Endpoint Classification: Efficacy Study

Intervention Model: Parallel Assignment

Masking: Double Blind (Subject, Caregiver)

Primary Purpose: Prevention

Official Title: Renal PRotection Against Contrast mEdium-induced nephroPathy in High Risk Patients undErgoing Coronary Angiography

Estimated Enrollment: 200

Study Start Date: June 2015

Estimated Study Completion Date: December 2017

Estimated Primary Completion Date: December 2016 (Final data collection date for primary outcome measure)

Arms:

Experimental: Remote Ischemic Preconditioning

Sham Comparator: Control