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Clinical trial

Personalising Anti-TNF Therapy in Crohns Disease (PANTS)

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Last updated:1st Mar 2013
Identifier: NCT03088449

To develop a cost-effective, individualised anti-TNF treatment strategy for patients with Crohn's disease which maximizes benefit and minimises harm.

The primary objective of this study is to investigate the mechanisms that underlie primary non-response (PNR), loss of response (LOR) and adverse drug reactions (ADRs) to anti-TNF drugs in patients with active luminal Crohn's disease.


Study Type: Observational
Actual Enrollment: 1750 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Investigation of the Clinical,Serological and Genetic Factors That Determine Primary Non-response, Loss of Response and Adverse Drug Reactions to Anti-TNF Drugs in Patients With Active Luminal Crohn's Disease
Study Start Date: March 2013
Primary Completion Date: July 30, 2017
Estimated Study Completion Date: July 30, 2019

Category Value
Date last updated at source 2017-12-05
Study type(s) Observational study
Expected enrolment 1750
Study start date 2013-03-01
Estimated primary completion date 2017-07-01

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