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Clinical trial

Neoadjuvant Triplet Chemotherapy Regimen in Patients With Resectable Colorectal Cancer

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Last updated:1st Mar 2014

Colorectal cancer is an aggressive malignancy with a poor overall outcome. The purpose of this study is to evaluate the feasibility, safety and efficacy of neoadjuvant oxaliplatin, irinotecan combined with 5-fluorouraci/leucovorin or S-1 or capecitabine in patients with resectable colorectal cancer.

Study Type: Interventional
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: A Pilot Phase II Study of Triplet Chemotherapy Regimen in Neoadjuvant Chemotherapy of Patients With Resectable Colorectal Cancer
Estimated Enrollment: 50
Study Start Date: March 2014
Estimated Study Completion Date: December 2019
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)

- Experimental:
single-arm Irinotecan-Oxaliplatin-5-Fluorouracil/leucovorin

Category Value
Study start date 2014-03-01

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