IReversible Electroporation of Kidney Tumors Before Partial Nephrectomy. (IRENE)

The aim of the study is the evaluation of the ablation efficiency of the percutaneous irreversible electroporation (IRE) as primary ablation therapy of locally confined renal cell carcinoma (?4cm, see inclusion and exclusion criteria). The ablation success will be proofed by magnet resonance imaging (MRI) and histologically after partial kidney resection or nephrectomy 4 weeks after IRE. Hypotheses: Kidney tumors ?4cm can be ablated completely by percutaneous IRE. Surrounded structures and renal tissue can be preserved.