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Clinical trial

FRactional Flow Reserve Versus Angiography-Guided Strategy for Management of Non-Infarction RElated Artery Stenosis in Patients With Acute ST-segment Elevation Myocardial Infarction (FRAME-STEMI)

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Last updated:1st Jun 2016

The aim of the study is to compare clinical outcomes following fractional flow reserve (FFR)-guided versus angiography only guided strategy in treatment of non-infarction related artery (non-IRA) stenosis in patients with acute ST-segment elevation myocardial infarction (STEMI) with multivessel disease

Prospective, open-label, randomized, multicenter trial to test the clinical outcomes following FFR-guided or angiography-guided strategy in treatment of non-IRA stenosis in patients with acute STEMI with multivessel disease.


Study Type: Interventional
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Comparison of Clinical Outcomes Between Fractional Flow Reserve-guided Strategy and Angiography-guided Strategy in Treatment of Non-Infarction Related Artery Stenosis in Patients With Acute ST-segment Elevation Myocardial Infarction
Estimated Enrollment: 974
Study Start Date: June 2016
Estimated Study Completion Date: December 2020
Estimated Primary Completion Date: June 2020 (Final data collection date for primary outcome measure)

Arms:
- Active Comparator:
FFR-guided strategy arm
- Active Comparator: Angiography-guided strategy arm

Category Value
Study start date 2016-06-01

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