Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery

Surgery is the primary treatment modality for many types of cancer and the extent of surgical resection is directly related to patient survival. However, it is often difficult for surgeons to distinguish normal from neoplastic tissue or to detect metastatic disease or tumor-infiltrated lymph nodes. In some sites, surgical precision is also required to avoid damage to critical normal tissues. The purpose of this exploratory study is to evaluate the ex vivo fluorescence of BLZ-100 in excised samples from subjects with various solid tumors including breast, lung, prostate, colorectal, and "other".
 

Study Type: Interventional

Intervention Model: Single Group Assignment

Official Title: A Phase 1 Exploratory Study of the Safety and ex Vivo Fluorescence of BLZ-100 Administered by Intravenous Injection in Adult Subjects With Solid Tumors Undergoing Surgery

Estimated Enrollment: 30

Study Start Date: July 2015

Estimated Study Completion Date: December 2015

Estimated Primary Completion Date: September 2015 (Final data collection date for primary outcome measure)

Arms: Experimental: BLZ-100