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Clinical trial

Computer Guided Doing of Tacrolimus in Renal Transplantation (OPTIMAL)

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Last updated:9th Dec 2013
Dosing of tacrolimus is challenging due to the large inter-individual variation in its pharmacokinetics. The investigators have developed a pharmacokinetics population model that can be used to estimate individual doses of tacrolimus in renal transplant recipients. The model will be prospective tested in a randomized clinical trial. The hypothesis is that the computer model is superior to experienced transplant physicians in reaching and keeping the patients in the target range of tacrolimus.
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Study start date 2013-12-09

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