Comparison of Two Titration Programs of Adding Insulin Detemir to OADs in Poorly Controlled Type 2 Diabetes

This study compared the effectiveness and safety of two treatment algorithms for insulin detemir initiation and titration: active titration algorithm (performed by investigator weekly) versus usual titration algorithm (performed by study subjects weekly) in patients with type 2 diabetes poorly controlled by OADs.

Study Type: Interventional

Allocation: Randomized

Endpoint Classification: Efficacy Study

Intervention Model: Parallel Assignment

Masking: Open Label

Primary Purpose: Treatment

Official Title: Comparison of Two Titration Programs of Adding Insulin Detemir to Oral Antidiabetic Drugs in Poorly Controlled Type 2 Diabetes Patients

Estimated Enrollment: 200

Study Start Date: January 2011

Estimated Study Completion Date: November 2015

Estimated Primary Completion Date: October 2015 (Final data collection date for primary outcome measure)
 

Arms:

Active Comparator: Active titration algorithm

titrate insulin dose by contacting with investigator by telephone weekly.

Experimental: Usual titration algorithm

contact with investigator only at routine study visit.