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Clinical trial

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

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Last updated:1st Jul 2011

This randomized phase III trial studies androgen-deprivation therapy and radiation therapy in treating patients with prostate cancer. Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. Radiation therapy uses high-energy x-rays to kill tumor cells.

Study Type: Interventional
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial
Estimated Enrollment: 2580
Study Start Date: July 2011
Estimated Primary Completion Date: July 2027 (Final data collection date for primary outcome measure)

- Active Comparator:
Arm I (IMRT, 3D-CRT)
- Experimental: Arm II (WPRT)

Category Value
Study start date 2011-07-01

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