An Open-label Study to Evaluate the Effect of Treatment With AMG 785 or Teriparatide in Postmenopausal Women (STRUCTURE)

This is a multi-center, randomized, open-label, TPTD-controlled study in postmenopausal women with osteoporosis at high risk for fracture.


Study Type: Interventional
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: An Open-label, Randomized, Teriparatide-controlled Study to Evaluate the Effect of Treatment With AMG 785 in Postmenopausal Women With Osteoporosis Previously Treated With Bisphosphonate Therapy
Enrollment: 436
Study Start Date: January 2013
Study Completion Date: May 2015
Primary Completion Date: May 2015 (Final data collection date for primary outcome measure)

Arms:
- Experimental: AMG 785
- Active Comparator: Teriparatide (TPTD)