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Clinical trial

Acetazolamide in Patients With Acute Heart Failure (ACETA)

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Last updated:1st Oct 2018
Identifier: NCT03720288

Introduction: Recent studies have suggested that the use of acetazolamide may assist in the vol- ume management of patients with decompensated heart failure (HF). However, prospective and randomized comparison in patients with HF and optimized diuretic therapy has not been described.

Objective: The aim of this study was to evaluate the effectiveness and safety of the use of acetazolamide versus placebo in volume control in patients with decompensated HF.

Methodology: For this, a unicentric, randomized, double blind and prospective study will be performed in a comparative manner. Hospital data (test results, medical outcomes, drug dose, complications) of patients will be analyzed for safety and effectiveness.

Expected results: The use of acetazolamide as an adjuvant treatment is superior to the standard strategy for volume control in patients with decompensated HF.

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 90 participants
Allocation : Randomized
Intervention Model : Parallel Assignment
Masking : Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose : Treatment
Official Title : Prospective Analysis Between Acetazolamide vs Placebo in Patients With Acute Heart Failure
Actual Study Start Date : October 1, 2018
Estimated Primary Completion Date : October 1, 2019
Estimated Study Completion Date : October 1, 2020

- Experimental:
- Experimental: Placebo

Category Value
Date last updated at source 2018-10-30
Study type(s) Interventional
Expected enrolment 90
Study start date 2018-10-01
Estimated primary completion date 2019-10-01

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