A Randomized, Double-Blind, 5-Arm, Parallel-Group, 26-Week, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Canagliflozin in Combination With Metformin as Initial Combination Therapy in the Treatment of Subjects With Type 2 Diabete

To assess the effect of the co-administration of canagliflozin and metformin XR compared with canagliflozin alone on HbA1c. To assess the effect of the co-administration of canagliflozin and metformin XR compared with metformin XR alone on HbA1c. To assess the safety and tolerability of the co-administration of canagliflozin and metformin XR, canagliflozin alone, and metformin XR alone.