A prospective, multicenter, open-label, patients with non-erosive gastroesophageal reflux disease (NERD) non-responders to therapy with PPIs

The prospective evaluation of the prevalence data - based on proper compliance, timing, type and dose of PPI - of NERD patients with typical symptoms (vs. atypical and extra-esophageal) resistant or poorly responsive to treatment with esomeprazole 40mg for 8 weeks / day