A Phase II, Double-Blind, Placebo Controlled, Randomised Study To Assess The Efficacy And Safety Of 2 Doses Of ZACTIMA (ZD6474) In Combination With FOLFOX vs FOLFOX Alone For The Treatment Of Colorectal Cancer In Patients Who Have Failed Therapy With An I

The primary objective of this study is to assess the efficacy of ZD6474 (100 mg and 300 mg) in combination with the modified FOLFOX 6 regimen (mFOLFOX6) versus mFOLFOX6 alone for the treatment of patients with colorectal cancer that have failed prior treatment with irinotecan and a fluoropyrimidine by assessment of disease progression.