Maintenance of Platelet Inhibition With Cangrelor (Bridge)

The purpose of this study is to demonstrate that patients receiving cangrelor infusion before coronary artery bypass grafting have an acceptable safety profile and can undergo surgery without excessive bleeding peri-operatively.


Study Type: Interventional
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: BRIDGE: Maintenance of Platelet inihiBition With cangRelor After dIscontinuation of ThienopyriDines in Patients Undergoing surGEry
Enrollment: 221
Study Start Date: October 2008
Study Completion Date: July 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)

Arms:
- Experimental: Cangrelor
- Placebo Comparator: Placebo


Related journal: Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: a randomized controlled trial.