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Anticoagulation Therapy for Stroke Prevention


Read time: 30 mins
Last updated:13th May 2022
Published:13th May 2022

The atrial fibrillation better care (ABC) pathway for stroke prevention

Watch selected highlights from the live ‘atrial fibrillation better care (ABC) pathway for stroke prevention’ webinar where expect faculty discuss the evidence and benefits of implementing the ABC pathway (Avoid stroke, Better symptom management, and Cardiovascular and comorbidity risk reduction) into clinical practice. The ABC pathway is now recommended in several clinical guidelines, including the recent European Society of Cardiology (ESC) AF management guidelines.

Better symptom management – Professor Dhiraj Gupta highlights

What do the ESC 2020 guidelines recommend as first-line intervention for rate control in patients with AF?

In the instance that rate control therapy is ineffective for managing AF, what is the next step?

Does early intervention with ablation improve quality of life for AF patients?


Avoiding stroke and comorbidity management – Professor Gregory Lip highlights

The 2020 ESC Guidelines for the diagnosis and management of AF using the ABC pathway

Which aspect of the ABC pathway is most important for stroke prevention?

What impact does adherence to the ABC pathway have on clinical outcomes for stroke prevention?


ABC pathway implementation – Professor Deirdre Lane highlights

What is integrated care for management of the patient with AF?

Does real-world evidence demonstrate the benefit of mobile-health technology in an integrated care framework?


Q & A session highlights

How would you manage a patient with intracranial haemorrhage who is receiving oral anticoagulants?

In patients where ablation has been successful, how would you continue to manage their risk of stroke?

Is there a scenario where you would ever use anticoagulation and antiplatelet drugs together in patients with AF?

What is the biggest challenge to clinical implementation and adherence to the ABC pathway?



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Professor Deirdre Lane PhD, FRCP (Edin), FESC, FHEA
Professor Deirdre Lane is Professor of Cardiovascular Health at the University of Liverpool and an Adjunct Professor of Cardiovascular Health at Aalborg University, Denmark. Her main research interest is atrial fibrillation, focused on bleeding and stroke risk stratification and patient-centred research. She is a co-author of the CHA2DS2-VASc and HAS-BLED scores. Her research also examines how AF affects quality of life and psychological well-being, patients’ perceptions of AF and medication adherence. She is a member of the Task Force for the 2020 European Society of Cardiology guidelines on the management of AF and the 2018 American College of Chest Physicians guidelines on antithrombotic therapy in AF patients. Her h-index is 91 and she has co-authored >300 peer-reviewed publications. She is currently rated as one of the top 10 world experts in atrial fibrillation by Expertscape.

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Professor Dhiraj Gupta, MBBS, MD, DM, FRCP, FESC

Professor Dhiraj Gupta is a consultant cardiologist at the Liverpool Heart and Chest Hospital (LHCH), which provides a regional electrophysiology (EP) service to a population of 2.8 million. Professor Gupta is a very high-volume operator in interventional EP and is the trust lead for its Left Atrial Appendage Occluder (LAAO) Service. He proctors cardiologists nationally and internationally for LAAO implants. Professor Gupta heads the arrhythmia work group of the Institute of Cardiovascular Medicine and Science, a research collaboration between Royal Brompton Hospital and LHCH and has been awarded NHS local Clinical Excellence Awards in 2010, 2014 and 2015, the national Bronze Clinical Excellence Award in 2016, and the national Silver Clinical Excellence Award in 2021.

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Professor Gregory Lip, MD

Professor Lip is Price-Evans Chair of Cardiovascular Medicine, at the University of Liverpool, UK – and Director of the Liverpool Centre for Cardiovascular Science at the University of Liverpool and Liverpool Heart & Chest Hospital. He is also Distinguished Professor at Aalborg University, Denmark; and Adjunct Professor at Seoul National University and Yonsei University, Seoul, Korea. Professor Lip has a major interest into the epidemiology of atrial fibrillation (AF), as well as the pathophysiology of thromboembolism in this arrhythmia. His introduction of the ABC (Atrial fibrillation Better Care) pathway streamlines AF patient management. The ABC pathway is now recommended in multiple clinical guidelines for stroke prevention.